Peptide sequencing plays a fundamental role in proteomics. Improving the efficiency and accuracy of sequencing algorithms is at the center of researches on peptide sequencing. Two important problems are charge determination of parent peptide ion and characterization of a set of spectrums. In this paper, we propose a linear time algorithm to accurately determine parent peptide charge, and study some useful characteristics for a set of spectra.

Nan Ye and Hon Wai Leong. Determining Charge State for Low Resolution Tandem Mass Spectra based on Complementary Peak Pairs. 2nd BioDM Workshop on Data Mining for Biomedical Applications (BioDM 2007)

        Download Paper