Main ongoing projects (IPAL-UMI CNRS)

  • MICO - COgnitive MIcroscope: A cognition-driven visual explorer for histopathology. Application to breast cancer grading.
    • Granted by the Technologies for Health program (TecSan - Technolgies pour la Sante) of the French National Research Agency (Agence Nationale de la Recherche - ANR).
    • Partners: IPAL/UJF, LIP6/UPMC, TRIBVN (SME Châtillon/Paris), THALES-TCF,  Pitié-Salpêtrière Hospital - Paris, AGFA Healthcare France
    • Personal role in the project: Principal Investigator,
    • Duration: 3 years (2011-2014)
    • Objectives:
      • The cognitive microscope (MICO) aims at radically modifying the medical practices by proposing a new cognitive medical imaging environment able to improve reliability of decision making in histopathology.
      • MICO aims at moving a step forward in medical practice by proposing the foundations of a new confluent cognitive medical imaging technology using context in intelligent way.
      • MICO behaves in a cognitively consistent way with standard medical practice, following a uniform representation of image analysis, reasoning and context elements.

  • IVS4NSC - "An Intelligent Vision System for Quantitative Microscopy in Neural Stem Cells Progenitor Growth and Differentiation"
    • Granted by A*STAR/JCO (Joint Council Office, A*STAR) Singapore
    • Partners: The project involves IPAL and three A*STAR institutes (Institute for Infocomm Research I2R/SERC, Bioinformatic Institute BII/BMRC and the Institute of Medical Biology IMB/BMRC)
    • Duration: 3,5 years (2009 – 2013)
    • Objectives:
      • The project aims to develop an intelligent vision system for the analysis of neural stem cells, their progenitors and cell differentiation; by integrating image processing and machine learning with microscopy to drive systematic high-throughput high-content screening to elucidate gene functions and signalling pathways.
      • The vital knowledge gained in this project can potentially be applied as therapeutics for the treatment of Central Nervous System diseases such as Parkinson's and Alzheimer's.
    • Related link: Image Informatics of Stem Cells

  • IMS – A suite of integrated microscopy systems for imaging anatomies of complex 3D cell culture systems
    • Project funded by A*STAR/JCO (Joint Council SERC-BMRC/A*STAR) Singapore
    • Involving IPAL and three A*STAR institutes (the Institute for Infocomm Research I2R/SERC, the Bioinformatic Institute BII/BMRC, the Institute of Molecular and Cell Biology IMCB/BMRC and the Institute of Medical Biology IMB/BMRC)
    • Duration: 3 years (2013 – 2016)

  • FlexMIm – collaborative digital histopathology
    • Funded by the Single Interministerial Fund (Fonds Unitaires Interministériels) French Ministry of Industry (MINEFE)
    • Project involving Orange Heathcare, Tribvn, Pertimm, the University Pierre and Marie Curie, the Univ. Paris Diderot and the Assistance publique – Hôpitaux de Paris, the public hospital system (établissement public de santé) of the city of Paris and its suburbs (AP-HP).
    • Role: Co-Principal Investigator and WP manager (Semantic and Imaging).
    • Duration: 3 years (2013-2016)

Major previous projects (IPAL UMI CNRS & FEMTO-ST UMR CNRS)

  • IC0604 - EURO-TELEPATH -“Telepathology Network in Europe”
    • COST Action European Cooperation in Science and Technology
    • Partners: Spain, France, Germany, Grece, Italy, Switzerland, Croatia, Finland, Lithuania, Nederland, Norway, Poland, Portugal, United Kingdom.
    • Duration: 4 years (2007-2011)
    • Domain : telepathology, virtual microscopy, histopathology

  • MMedWeb "Multimedia Medical Conceptual Web for Intelligent Information Access"
    • Granted by A*STAR/SERC - Science & Engineering Research Council, Agency for Science, Technology and Research, Singapore
    • Partners: CNRS, NUS, I2R/A*STAR, Nat. Univ. Hospital (NUH), National Healthcare Group, Singapore General Hospital (SGH)
    • Personal role in the project; Co-Principal Investigator
    • Duration: 3 years (2007-2010)
    • Objectives:
      • Developing a framework for the semantic structuring and organization of multimedia medical information (images, reports).
      • Implementing a prototype system of the framework with user-friendly network tools for navigation and query of MMedWeb.
      • Trial integration of MMedWeb with existing medical databases (PACS, RIS, etc.)

  • ONCO-MEDIA "Ontology and COntext related MEdical image Distributed Intelligent Access"
    • Funded by the 5th ICT-ASIA Programme (France / Asia)
    • International partners from Singapore (IPAL), France (CREATIS, LIRIS, LIP6, IS3, FEMTO-ST), Switzerland (UNIGE), Taiwan (NTU), Philippine (ATENEO), Japan (CIGG);
    • Personal role in the project: Principal Investigator
    • Duration: 2 years (2006-2007 and 2009-2010)
    • Objctives:
      • To develop a novel grid-distributed, contextual and semantic based, intelligent information access framework for medical images and associated medical reports;
      • To explore new medical image diagnosis assistance, teaching and research access applications using semantic, visual and context-sensitive medical information with the grid computing facilities;
      • To crystallize a network of research excellence in the field of distributed medical images access among Asia, French and French Switzerland partners, leveraging on their complementary scientific values and experience.
  • PROTEUS - A Generic Platform for E-maintenance,
    • FP5 European Integrated Project of ITEA program (Information Technology for European Advancement)
    • Duration : 3 years (2002-2005)
    • 14 European industrial and academic partners (France; Germany, Belgium) : CEGELEC, AKN, Univ. Munich, LORIA-INRIA/CNRS, LIP6/UPMC, FEMTO-ST/UFC, LIFC/UFC, Pertinence Data ...

  • NEMOSYS - Naval E-Maintenance Oriented SYStem;
    • Research contract with DCNS Direction des Constructions Navales Services, France.
    • Duration: 2 years (2004-2006), Role of FEMTO-ST : PI
    • 6 French industrial and academic partners of GdR MACS, GT MACOD: FEMTO-ST/UFC, CEGELEC, CRAN, UTT, ...
    • Scope: diagnostic, prognostic and dynamic monitoring.
    • This collaboration allowed the vreation in 2007 of the spin-off
      e-m@systec, at the TEMIS incubation, Besançon.