Data Mining Algorithms for Pharmacogenomics

Participants: Pauline Chen, Coral Lai, Tze Yun Leong, Lin Li, Guimei Liu, Yue Wang, Limsoon Wong.


Human genome harbors millions of common single nucleotide polymorphisms (SNPs) and other types of genetic variations. These genetic variations play an important role in understanding the correlation between genetic variations and human diseases and the body's responses to prescribed drugs. The discovery of such genetic factors contributing to variations in drug response, efficiency, and toxicity has come to be known as pharmacogenomics. In this project, we explore several pharmacogenomic-related applications of database and datamining technologies.


Selected Publications


Selected Presentations


This project is supported in part by NUS ARF grant R-252-050-238-101/133 (Wong: 11/05 - 11/08), SERC PSF grant 072-101-0016 (Liu, Wong: 8/07 - 12/10), and an NGS scholarship (Wang).

Last updated: 13/8/13, Limsoon Wong.