Click here to visit the IVLE course webpage (that is the main page).
Computational Biology is a fast changing area. In the post-genome era, many new bio-technologies appear and classical algorithms for computational biology are no longer enough. This module is intended to cover the important algorithms related to the new technologies like microarray, SNPs, mass spectrometry, etc.
After the complete sequencing of a number of genomes, we are in the stage to understand the mystery of our body, that is, we need to understand the information encoded in the genome and its relationship with RNA and protein. This aim of this module is to cover the algorithms related to this stage.
In the module, we will cover the algorithms related to phylogenetic, RNA, proteomics, population genetics, microarray, etc.
Prerequisites: Pass CS2220 (Introduction to Computational Biology) or its equivalence.
|1||15 Jan 2014||Basic of Molecular Biology and Biotechnology||Chapter 1 of the main text|
|2||22 Jan 2014||Phylogenetic comparsion and consensus tree||Chapter 8 of the main text|
|3||29 Jan 2014||Phylogenetic comparsion and consensus tree||Chapter 8 of the main text, Consensus Tree (SODA2013) Majority-rule consensus tree (RECOMB2013)|
|4||5 Feb 2014||Whole genome alignment||Chapter 4 of the main text, MSS|
|5||12 Feb 2014||Genome rearrangement (unsigned reversal distance)||Chapter 9 of the main text|
|6||19 Feb 2014||Genome rearrangement (signed reversal distance)||Chapter 9 of the main text|
|26 Feb 2014||Recess week|
|7||5 Mar 2014||Term test and Population genetics||Chapter 13 of the main text|
|8||12 Mar 2014||Population genetics||Chapter 13 of the main text, Reference for CF data Reference on EM algorithm|
|9||19 Mar 2014||Population genetics||Chapter 13 of the main text, Association_study_Nature_Reviews2006|
|10||26 Mar 2014||Peptide sequencing||Chapter 12 of the main text|
|11||2 Apr 2014||RNA Secondary Structure||Chapter 11 of the main text|
|12||9 Apr 2014||Pathogen Chip and Differential expressed gene||pathogen_chip_Genome_Bio2007, LOMA2008, PEM_jbcb2006|
|13||16 Apr 2014||Project Presentation|
|7 May 2014||Examination Week|