Consider this Genpept report from Entrez:
LOCUS T41727 577 aa PLN 03-DEC-1999
DEFINITION F-box domain protein Pof3p - fission yeast (Schizosaccharomyces
pombe).
ACCESSION T41727
PID g7490551
VERSION T41727 GI:7490551
DBSOURCE pir: locus T41727;
summary: #length 577 #molecular-weight 66238 #checksum 7366;
genetic: #gene pof3; SPDB:SPCC338.16 #map_position 3;
PIR dates: 03-Dec-1999 #sequence_revision 03-Dec-1999 #text_change
03-Dec-1999.
KEYWORDS .
SOURCE fission yeast.
ORGANISM Schizosaccharomyces pombe
Eukaryota; Fungi; Ascomycota; Schizosaccharomycetales;
Schizosaccharomycetaceae; Schizosaccharomyces.
REFERENCE 1 (residues 1 to 577)
AUTHORS Lyne,M., Wood,V., Rajandream,M.A., Barrell,B.G., Murphy,L. and
Harris,D.
TITLE Direct Submission
JOURNAL Submitted (??-JUN-1998) to the EMBL Data Library
FEATURES Location/Qualifiers
source 1..577
/organism="Schizosaccharomyces pombe"
/db_xref="taxon:4896"
Protein 1..577
/product="F-box domain protein Pof3p"
ORIGIN
1 mnnyqvkaik ektqqylskr kfedaltfit ktieqepnpt idlfelraqv yeksgqysqa
61 eldakrmihl narnargylr lgkllqldgf dkkadqlytq glrmvhkmdp lrpvlkkvsq
121 rlnerilrtr pvldlfrilp revllcilqq lnfksivqcm qvckhwrdci kkepslfccl
181 dfscasprsv nsrdrnvmav arysvyskdn iqeviglekl giltptkall rsvkslkvyk
241 tisplhtqst dklytiwtpf selhyfycat pitfsiaski lscckklkqv elvdlipdli
301 fdsmdwdklf naesvplalk sltfirnqkf pfhhkeqqfl kdllsaspyl eyleasyqsd
361 lvaaikkyki nlrsliiide gvsntvkdla flpqslttli vkpcnpasti lcpylfptnv
421 rmeslinlel flylrlsqnd idnvvkflts cyklkklvlh dslalaphff eifaslpele
481 hleipdnval qnkhaihitd ccpnlkyvnf snsisldgsg fiavlrglke lkridiincd
541 svsrdaidwa rskgmqvtva sslpnsqplg tkkirli
//
What are the lexical, logical, and semantics layers?
Is this exchange format well-designed?
What are its weaknesses
Consider this Medline ``abstract'' from Entrez:
1: Plant J 1999 Dec;20(6):641-52 The tomato I-box binding factor LeMYBI is a member of a novel class of myb-like proteins. Rose A, Meier I, Wienand U Institut fur Allgemeine Botanik, Universitat Hamburg, Ohnhorststr. 18, D-22609 Hamburg, Germany. The RBCS3A gene of tomato belongs to a small gene family consisting of five members. Although the RBCS1, RBCS2 and RBCS3A promoters contain closely related cis regulatory sequences, the expression patterns of the genes are different. Whereas the RBCS1 and RBCS2 genes are expressed in both leaves and young fruit, the RBCS3A promoter is highly active in leaves, but not in young fruit. This lack of transcription could be due to a mutation in the RBCS3A promoter creating the so-called F-box, a protein binding site located between the activating cis elements, the I-box and G-box. In order to identify proteins that bind to the RBCS3A I-box/F-box region, the yeast one-hybrid system was used. One clone, LeMYBI was isolated which contains strong similarity to plant myb transcription factors. The encoded LeMYBI protein is at least 188 amino acids in length and contains two myb-like domains located at the amino terminus and close to the carboxy terminus, separated by a negatively charged domain. The protein contains a SHAQKYF amino acid signature motif in the second myb-like repeat, which is highly conserved in a number of recently identified plant myb-related genes, thus defining a new class of plant DNA-binding proteins. LeMYBI binds specifically to the I-box sequence of the RBCS1, RBCS2 and RBCS3A promoters, therefore representing the first cloned I-box binding factor. LeMYBI acts as a transcriptional activator in yeast and plants, and binds to the I-box with a DNA-binding domain located in the carboxyterminal domain. PMID: 10652136, UI: 20117515 What are the lexical, logical, and semantics layers? Is this exchange format well-designed? What are its weaknesses